Development of Poly(Vinyl Alcohol) Cryo-Systems with Medicines and Their Comparative Study of Antimicrobial Activity and Cytotoxicity

IFMBE Proceedings. Vol.38: International Symposium on Biomedical Engineering and Medical Physics 2013
Jolanta Staško, Nadežda Romančikova, Aigars Reinis, Līga Bērziņa-Cimdiņa, Juta Kroica

The aim of the work was to develop the poly(vinyl alcohol) cryogel systems (PVAGS) with plant extracts (PPe) and simple conventional medicine (Cm), and compare their antimicrobial activity, biocompatibility and cytotoxicity. The stability of gels systems with and without medicines was determined, the gel content and swelling degree were calculated. In vitro studies of PVAGS, with and without medicines, microbial contamination risk – the colonization level of the microorganisms and adhesion activity for the use of gel materials for the wound care were detected. PVAGS biocompatibility and cytotoxic properties were examined on cell lines.

Atslēgas vārdi
poly(vinyl alcohol); cryogel systems; cytotoxicity; biocompatibility; microbial adherence
DOI
10.1007/978-3-642-34197-7_30
Hipersaite
http://link.springer.com/chapter/10.1007%2F978-3-642-34197-7_30?LI=true

Staško, J., Romančikova, N., Reinis, A., Bērziņa-Cimdiņa, L., Kroica, J. Development of Poly(Vinyl Alcohol) Cryo-Systems with Medicines and Their Comparative Study of Antimicrobial Activity and Cytotoxicity. No: IFMBE Proceedings. Vol.38: International Symposium on Biomedical Engineering and Medical Physics, Latvija, Rīga, 11.-12. oktobris, 2012. Berlin: Springer Berlin Heidelberg, 2013, 113.-118.lpp. ISBN 978-3-642-34196-0. e-ISBN 978-3-642-34197-7. ISSN 1680-0737. Pieejams: doi:10.1007/978-3-642-34197-7_30

Publikācijas valoda
English (en)