Development of Poly(Vinyl Alcohol) Cryo-Systems with Medicines and Their Comparative Study of Antimicrobial Activity and Cytotoxicity

Riga Technical University 53rd International Scientific Conference: Dedicated to the 150th Anniversary and the 1th Congress of World Engineers and Riga Polytechnical Institute/ RTU Alumni: Digest 2012
Jolanta Staško, Nadežda Romančikova, Aigars Reinis, Līga Bērziņa-Cimdiņa, Juta Kroica

The aim of the work was to develop the poly(vinyl alcohol) cryogel systems (PVAGS) with plant extracts (PPe) and simple conventional medicine (Cm), and compare their antimicrobial activity, biocompatibility and cytotoxicity. The stability of gels systems with and without medicines was determined, the gel content and swelling degree were calculated. In vitro studies of PVAGS, with and without medicines, microbial contamination risk – the colonization level of the microorganisms and adhesion activity for the use of gel materials for the wound care were detected. PVAGS biocompatibility and cytotoxic properties were examined on cell lines.

Atslēgas vārdi
poly(vinyl alcohol); cryogel systems; cytotoxicity; biocompatibility; microbial adherence
Hipersaite
http://scientific-conference2012.rtu.lv/sites/default/files/pdf/RTU_Conference_2012.pdf

Staško, J., Romančikova, N., Reinis, A., Bērziņa-Cimdiņa, L., Kroica, J. Development of Poly(Vinyl Alcohol) Cryo-Systems with Medicines and Their Comparative Study of Antimicrobial Activity and Cytotoxicity. No: Riga Technical University 53rd International Scientific Conference: Dedicated to the 150th Anniversary and the 1th Congress of World Engineers and Riga Polytechnical Institute/ RTU Alumni: Digest, Latvija, Riga, 11.-12. oktobris, 2012. Riga: RTU, 2012, 739.-739.lpp. ISBN 978-9934-10-360-5.

Publikācijas valoda
English (en)