The Paper provides preliminary results with the aim to determine a range of the local scientific activity in the development of advanced technologies on a global scale. Analysis on ranking is made in the Baltic Sea Region accepted as the main limitation of the Paper. The applied methods are logical approach, analysis of the literary sources, assessment of the indicators (including financing, scientific and innovative activities ratios), its dynamics in the scientific field and business arena. The enclosed analytical data ensure the value of the Paper. Among the main findings are: available data for the economic assessment of the nanotechnologies in Latvia are of a general character, limited or controversial. Recently, Latvia has had both the lowest and the highest rankings.