The aim of this work was to evaluate the effect of precursor materials used in the synthesis on the Sr incorporation levels into the hydroxyapatite (HAp) lattice and to characterize the synthesis products. HAp powders containing various amounts of Sr were synthesized through three different precipitation routes. In all cases, the as-synthesized products were found to be pure HAp. However, atomic absorption spectrometry analysis showed that by reacting orthophosphoric acid with calcium hydroxide and strontium hydroxide, as well as by reacting diammonium hydrogen phosphate with calcium nitrate tetrahydrate and strontium nitrate a significant proportion of the Sr added, did not substitute into the HAp lattice. X-ray diffraction analysis revealed that the effect of substituting relatively high amounts (up to 3.69 ± 0.37 wt.%) of Sr into the HAp lattice was to decrease the cristallinity. Brunauer-Emmett-Teller (nitrogen absorption) analysis showed that the incorporation of Sr reduced particle sizes of the precipitated HAp products. Contrary, scanning electron microscopy revealed that the incorporation of Sr increased length of the precipitated needle-like particles.