Peptidic α-ketoamides as PfSUB1 Inhibitors

Balticum Organicum Syntheticum (BOS 2018): Program and Abstracts 2018
Elīna Līdumniece, Aigars Jirgensons

We have developed peptidic PfSUB1 inhibitors containing α-ketoamide warhead. Preliminary SAR investigations revealed the crucial interactions of ketoamide inhibitors. Here we report additional studies to explore the optimal substituents for sub-pockets.

Atslēgas vārdi
PfSUB, inhibitors, α-ketoamide

Līdumniece, E., Jirgensons, A. Peptidic α-ketoamides as PfSUB1 Inhibitors. No: Balticum Organicum Syntheticum (BOS 2018): Program and Abstracts, Tallinn, 1.-4. jūlijs, 2018. Tallinn: 2018, 95.-95.lpp.

Publikācijas valoda
English (en)