RTU Zinātniskās darbības rezultāti un resursi: Personāls

Informācija par autoru

Vārds, Uzvārds:

Aigars Jirgensons

Struktūrvienība:

(32300) Ķīmijas un ķīmijas tehnoloģijas institūts

Zinātniskais grāds:

Doktors

E-pasts:

Aigars.Jirgensons(at)rtu.lv

Publikācijas

Atrasti 132 rezultāti tiek attēloti no 1 līdz 10.

Discovery of Malarial Threonyl tRNA Synthetase Inhibitors by Screening of a Focused Fragment Library
(2024)

Jekaterina Boļšakova, Raitis Bobrovs, Larisa Varacheva, Anastasija Rudnickiha, Iveta Kaņepe, Emilio Parisini, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors
(2023)

Raitis Bobrovs, LAURA RUDUŠA, Iveta Kaņepe, Aigars Jirgensons, Amedeo Caflisch, Matteo Salvalaglio, Kristaps Jaudzems
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Semisynthesis of Linariophyllenes A-C and Rumphellolide H, Structure Revisions and Proposed Biosynthesis Pathways
(2023)

Georgijs Stakanovs, Anastasija Blazevica, Sergey Belyakov, Dace Rasiņa, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
(2023)

Vadims Kovada, Chrislaine Withers-Martinez, Raitis Bobrovs, Helēna Cīrule, Edgars Liepiņš, Solveiga Grinberga, Fiona Hackett, Christine R. Collins, Agrita Kreicberga, Maria Belen Jimez-Diaz, Inigo Angulo-Barturen, Dace Rasiņa, Edgars Sūna, Kristaps Jaudzems, Michael J. Blackman, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Assembling the Methanoindene Cage of Phragmalin-Type Natural Products
(2023)

Joseph Becica, Olavs Rāciņš, Marija Ivanova, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Synthesis and Evaluation of an Agrocin 84 Toxic Moiety (TM84) Analogue as a Malarial Threonyl tRNA Synthetase Inhibitor
(2023)

Jhon Alexander Rodriguez Buitrago, Gundars Leitis, Iveta Kaņepe-Lapsa, Anastasija Rudnickiha, Emilio Parisini, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors
(2023)

Olga Bobileva, Raitis Bobrovs, Evelīna Elva Sirma, Iveta Kaņepe, Anna L. Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Effect of Novel Furan-Based Ester Reactive Diluent on Structure and Properties of UV-Crosslinked Acrylated Rapeseed Oil
(2023)

Sabīne Briede, Oskars Platnieks, Madara Dārziņa, Aigars Jirgensons, Sergejs Gaidukovs
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Synthesis and SAR of Phenylazoles, Active Against Staphylococcus Aureus Newman
(2023)

Vitalii Solomin, Blanca Fernandez Ciruelos, Nadya Velikova, Jerry Wells, Marco Albanese, Adhav Anmol, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Subtilisin-like Serine Protease 1 (SUB1) as an Emerging Antimalarial Drug Target: Current Achievements in Inhibitor Discovery
(2022)

Elīna Līdumniece, Chrislaine Withers-Martinez, Fiona Hackett, Michael J Blackman, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Informācija par autoru

Publikācijas

Discovery of Malarial Threonyl tRNA Synthetase Inhibitors by Screening of a Focused Fragment Library
(2024)

Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors
(2023)

Semisynthesis of Linariophyllenes A-C and Rumphellolide H, Structure Revisions and Proposed Biosynthesis Pathways
(2023)

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
(2023)

Assembling the Methanoindene Cage of Phragmalin-Type Natural Products
(2023)

Synthesis and Evaluation of an Agrocin 84 Toxic Moiety (TM84) Analogue as a Malarial Threonyl tRNA Synthetase Inhibitor
(2023)

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors
(2023)

Effect of Novel Furan-Based Ester Reactive Diluent on Structure and Properties of UV-Crosslinked Acrylated Rapeseed Oil
(2023)

Synthesis and SAR of Phenylazoles, Active Against Staphylococcus Aureus Newman
(2023)

Subtilisin-like Serine Protease 1 (SUB1) as an Emerging Antimalarial Drug Target: Current Achievements in Inhibitor Discovery
(2022)

Vadītie promocijas darbi

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Stannilmetilēteru un furāna atvasinājumu elektroķīmiska oksidēšana jaunu sintēzes metožu izveidei
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Elektrofīlu inducētas ciklopropānu reakcijas ar nukleofīliem
(2018)

Malārijas aspartilproteināžu inhibitoru izveide
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-heteroatoms saites izveidošana luisa skābes katalizētās aliliskās aizvietošanas reakcijās
(2013)

Projekti

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika

Informācija par autoru

Publikācijas

Discovery of Malarial Threonyl tRNA Synthetase Inhibitors by Screening of a Focused Fragment Library (2024)

Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors (2023)

Semisynthesis of Linariophyllenes A-C and Rumphellolide H, Structure Revisions and Proposed Biosynthesis Pathways (2023)

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity (2023)

Assembling the Methanoindene Cage of Phragmalin-Type Natural Products (2023)

Synthesis and Evaluation of an Agrocin 84 Toxic Moiety (TM84) Analogue as a Malarial Threonyl tRNA Synthetase Inhibitor (2023)

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors (2023)

Effect of Novel Furan-Based Ester Reactive Diluent on Structure and Properties of UV-Crosslinked Acrylated Rapeseed Oil (2023)

Synthesis and SAR of Phenylazoles, Active Against Staphylococcus Aureus Newman (2023)

Subtilisin-like Serine Protease 1 (SUB1) as an Emerging Antimalarial Drug Target: Current Achievements in Inhibitor Discovery (2022)

Vadītie promocijas darbi

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors (2023)

Stannilmetilēteru un furāna atvasinājumu elektroķīmiska oksidēšana jaunu sintēzes metožu izveidei (2023)

Development of Malarial Enzyme Inhibitors (2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase (2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols (2020)

Elektrofīlu inducētas ciklopropānu reakcijas ar nukleofīliem (2018)

Malārijas aspartilproteināžu inhibitoru izveide (2016)

Development of Malarial Protease PfSUB1 Inhibitors (2014)

C-heteroatoms saites izveidošana luisa skābes katalizētās aliliskās aizvietošanas reakcijās (2013)

Projekti

Atbalsts RTU doktora studiju īstenošanai - 2 Izglītība

Methods of critical infrastructure control Enerģētika

Discovery of Malarial Threonyl tRNA Synthetase Inhibitors by Screening of a Focused Fragment Library
(2024)

Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors
(2023)

Semisynthesis of Linariophyllenes A-C and Rumphellolide H, Structure Revisions and Proposed Biosynthesis Pathways
(2023)

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
(2023)

Assembling the Methanoindene Cage of Phragmalin-Type Natural Products
(2023)

Synthesis and Evaluation of an Agrocin 84 Toxic Moiety (TM84) Analogue as a Malarial Threonyl tRNA Synthetase Inhibitor
(2023)

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors
(2023)

Effect of Novel Furan-Based Ester Reactive Diluent on Structure and Properties of UV-Crosslinked Acrylated Rapeseed Oil
(2023)

Synthesis and SAR of Phenylazoles, Active Against Staphylococcus Aureus Newman
(2023)

Subtilisin-like Serine Protease 1 (SUB1) as an Emerging Antimalarial Drug Target: Current Achievements in Inhibitor Discovery
(2022)

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Stannilmetilēteru un furāna atvasinājumu elektroķīmiska oksidēšana jaunu sintēzes metožu izveidei
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Elektrofīlu inducētas ciklopropānu reakcijas ar nukleofīliem
(2018)

Malārijas aspartilproteināžu inhibitoru izveide
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-heteroatoms saites izveidošana luisa skābes katalizētās aliliskās aizvietošanas reakcijās
(2013)

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika