RTU Zinātniskās darbības rezultāti un resursi: Personāls

Informācija par autoru

Vārds, Uzvārds:

Aigars Jirgensons

Struktūrvienība:

(32300) Ķīmijas un ķīmijas tehnoloģijas institūts

Zinātniskais grāds:

Doktors

E-pasts:

Aigars.Jirgensons(at)rtu.lv

Publikācijas

Atrasti 144 rezultāti tiek attēloti no 31 līdz 40.

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening
(2021)

R Bobrovs, I Kaņepe, N Narvaiss, L Patetko, G Kalniņš, M Sisovs, A.L Bula, S Grīnberga, M Borodušķis, A Ramata-Stunda, N Rostoks, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids
(2020)

V.V. Solomin, A. Seins, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Friedel–Crafts Alkylation with Carbenium Ions Generated by Electrochemical Oxidation of Stannylmethyl Ethers
(2020)

Anna Lielpētere, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

A Concise Bioinspired Semisynthesis of Rumphellaones A-C and Their C-8 Epimers from β-Caryophyllene
(2020)

Georgijs Stakanovs, Anatolijs Mišņovs, Dace Rasiņa, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency
(2020)

Dace Rasiņa, Georgijs Stakanovs, Iveta Kaņepe-Lapsa, Raitis Bobrovs, Kristaps Jaudzems, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Exploiting Structural Dynamics to Design Open-Flap Inhibitors of Malarial Aspartic Proteases
(2019)

R. Bobrovs, Kristaps Jaudzems, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
(2019)

Aigars Jirgensons, un 37 līdzautori
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Amination of Carbenium Ions Generated by Directed Protonolysis of Cyclopropane
(2019)

Marija Skvorcova, Tomass Lūkass Lukaševics, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Refining the Structure−Activity Relationships of 2-Phenylcyclopropane Carboxylic Acids as Inhibitors of O-Acetylserine Sulfhydrylase Isoforms
(2019)

J. Magalhaes, N. Franko, G. Annunziato, M. Pieroni, R. Benoni, Anna Nikitjuka, A. Mozzarelli, S. Bettali, A. Karawajczyk, Aigars Jirgensons, B. Campanini, G. Constantino
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D
(2019)

R. Zogota, L. Kinena, C. Withers-Martinez, M.J. Blackman, R. Bobrovs, T. Pantelejevs, I. Kanepe-Lapsa, V. Ozola, Kristaps Jaudzems, Edgars Sūna, Aigars Jirgensons
Zinātniskais raksts, kas indeksēts Web of science un/vai Scopus datu bāzē

Informācija par autoru

Publikācijas

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening
(2021)

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids
(2020)

Friedel–Crafts Alkylation with Carbenium Ions Generated by Electrochemical Oxidation of Stannylmethyl Ethers
(2020)

A Concise Bioinspired Semisynthesis of Rumphellaones A-C and Their C-8 Epimers from β-Caryophyllene
(2020)

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency
(2020)

Exploiting Structural Dynamics to Design Open-Flap Inhibitors of Malarial Aspartic Proteases
(2019)

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
(2019)

Amination of Carbenium Ions Generated by Directed Protonolysis of Cyclopropane
(2019)

Refining the Structure−Activity Relationships of 2-Phenylcyclopropane Carboxylic Acids as Inhibitors of O-Acetylserine Sulfhydrylase Isoforms
(2019)

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D
(2019)

Vadītie promocijas darbi

Eksotisku terpenoīdu sintēze no (–)-β-kariofilēna
(2024)

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Stannilmetilēteru un furāna atvasinājumu elektroķīmiska oksidēšana jaunu sintēzes metožu izveidei
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Elektrofīlu inducētas ciklopropānu reakcijas ar nukleofīliem
(2018)

Malārijas aspartilproteināžu inhibitoru izveide
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-heteroatoms saites izveidošana luisa skābes katalizētās aliliskās aizvietošanas reakcijās
(2013)

Projekti

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika

Informācija par autoru

Publikācijas

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening (2021)

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids (2020)

Friedel–Crafts Alkylation with Carbenium Ions Generated by Electrochemical Oxidation of Stannylmethyl Ethers (2020)

A Concise Bioinspired Semisynthesis of Rumphellaones A-C and Their C-8 Epimers from β-Caryophyllene (2020)

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency (2020)

Exploiting Structural Dynamics to Design Open-Flap Inhibitors of Malarial Aspartic Proteases (2019)

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology (2019)

Amination of Carbenium Ions Generated by Directed Protonolysis of Cyclopropane (2019)

Refining the Structure−Activity Relationships of 2-Phenylcyclopropane Carboxylic Acids as Inhibitors of O-Acetylserine Sulfhydrylase Isoforms (2019)

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D (2019)

Vadītie promocijas darbi

Eksotisku terpenoīdu sintēze no (–)-β-kariofilēna (2024)

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors (2023)

Stannilmetilēteru un furāna atvasinājumu elektroķīmiska oksidēšana jaunu sintēzes metožu izveidei (2023)

Development of Malarial Enzyme Inhibitors (2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase (2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols (2020)

Elektrofīlu inducētas ciklopropānu reakcijas ar nukleofīliem (2018)

Malārijas aspartilproteināžu inhibitoru izveide (2016)

Development of Malarial Protease PfSUB1 Inhibitors (2014)

C-heteroatoms saites izveidošana luisa skābes katalizētās aliliskās aizvietošanas reakcijās (2013)

Projekti

Atbalsts RTU doktora studiju īstenošanai - 2 Izglītība

Methods of critical infrastructure control Enerģētika

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening
(2021)

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids
(2020)

Friedel–Crafts Alkylation with Carbenium Ions Generated by Electrochemical Oxidation of Stannylmethyl Ethers
(2020)

A Concise Bioinspired Semisynthesis of Rumphellaones A-C and Their C-8 Epimers from β-Caryophyllene
(2020)

Synthesis of 2-Aminopyridopyrimidinones and Their Plasmepsin I, II, IV Inhibition Potency
(2020)

Exploiting Structural Dynamics to Design Open-Flap Inhibitors of Malarial Aspartic Proteases
(2019)

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
(2019)

Amination of Carbenium Ions Generated by Directed Protonolysis of Cyclopropane
(2019)

Refining the Structure−Activity Relationships of 2-Phenylcyclopropane Carboxylic Acids as Inhibitors of O-Acetylserine Sulfhydrylase Isoforms
(2019)

Peptidomimetic Plasmepsin Inhibitors with Potent Anti-Malarial Activity and Selectivity against Cathepsin D
(2019)

Eksotisku terpenoīdu sintēze no (–)-β-kariofilēna
(2024)

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Stannilmetilēteru un furāna atvasinājumu elektroķīmiska oksidēšana jaunu sintēzes metožu izveidei
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Elektrofīlu inducētas ciklopropānu reakcijas ar nukleofīliem
(2018)

Malārijas aspartilproteināžu inhibitoru izveide
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-heteroatoms saites izveidošana luisa skābes katalizētās aliliskās aizvietošanas reakcijās
(2013)

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika