To design energy efficient buildings it is not only important to achieve well- balanced energy consumption but to provide high parameters of the indoor quality and thermal comfort as well as to minimize environmental impact. Only comprehensive analysis of many factors such as thermal insulation, HVAC systems, eco-friendly materials, sustainable architectural design makes possible to obtain such results. This research is devoted to one of the most important parameters such as thermal insulation and ventilation, which have effect on both the indoor air quality and building's energy efficiency. This study focuses on making energy consumption analysis in major cities of Baltic-sea region. This study covers City of Riga, City of Tallinn, City of Helsinki and Saint Petersburg. Currently Saint Petersburg's region construction market is significantly growing up. The energy performance requirements have many differences in comparison with Baltic countries with similar climatic conditions. The main reason are low fossil fuel's prices. However, international leading construction companies are looking forward to implementing EU best practice experience in Russia. The main goal of this study is to prove that the Baltic Sea region energy efficiency standards can be implemented in St. Petersburg's region. The paper provides comparison of country's requirements of building's energy efficiency and how the application of different standards in combination with ventilation alternatives in each analyzed city affects annual energy consumption in St. Petersburg's region. The IDA-ICE 4.7 dynamic simulation software was used to make evaluation of each country normative requirement effect on building energy consumption in different Baltic-sea region.