Ring Opening Reactions of Fused Tetrazolopyrimidines

Balticum Organicum Syntheticum 2022: Program and Abstract Book 2022
Jānis Miķelis Zaķis, Zigfrīds Kapilinskis, Dinesh Kumar, Anna Dozorina, Jurijs Renārs Vērdiņš, Anatolijs Mišņovs, Irina Novosjolova, Māris Turks

Purine derivatives can be opened at both pyrimidine and imidazole rings.1 In our research we focused on investigation and optimization of ring opening reactions in fused pyrimidines based on azido-tetrazole equilibrium. Under nucleophile attack the pyrimidine ring opened, forming tetrazolyl derivatives 2a-c. The structures were proved by X-ray analysis.

Atslēgas vārdi
tetrazolopyrimidines, ring opening

Zaķis, J., Kapilinskis, Z., Kumar, D., Dozorina, A., Vērdiņš, J., Mišņovs, A., Novosjolova, I., Turks, M. Ring Opening Reactions of Fused Tetrazolopyrimidines. No: Balticum Organicum Syntheticum 2022: Program and Abstract Book, Lietuva, Vilnius, 3.-6. jūlijs, 2022. Vilnius: 2022, 135.-135.lpp.

Publikācijas valoda
English (en)