Bacteria regrowth in water distribution networks is an issue that has been addressed by many authors. Significant efforts were made to develop a com- prehensive model for simulating growth of bacteria in drinking water distribution networks. Although bacteria development is affected by many factors and it is vir- tually impossible to take them all into account, there were attempts to determine the most significant factors influencing bacteria growth. A mathematical model de- scribing growth of bacteria in water distribution pipes is proposed in [8]. In the present paper the model is incorporated into Epanet-MSX software. The Epanet- MSX model is tested and the results obtained are compared with an experimentally validated model results and the results obtained in [8] by alternating split-operator technique. Straight pipe and a simple network are used as a platform for testing the model for various conditions and parameters. Epanet-MSX does not take dispersion into account, so the dispersion term is excluded. The results obtained with the vali- dated model and the results of [8] agree well with the results of Epanet-MSX model for a certain range of parameters.