Triazolylmethyl Aziridines with Various Side Chain
Latvijas Ķīmijas Žurnāls 2012
Jānis Zemītis, Imants Kreituss, Māris Turks, Ērika Bizdēna, Peteris Trapencieris

More than hundred compounds from aziridine class shown certain biological activity. We report here the synthesis of racemic version of protected azidomethyl aziridine via easily accessible intermediates. Further, small combinatorial library of triazolylmethyl aziridines was obtained by CuAAC reaction and deprotection. To the best of our knowledge such aziridine derivatives have not been tested for their biological activities. Comparison of synthesis of racemic and enantiomerically pure series of products and their biological activities will be discussed.


Atslēgas vārdi
triazolylmethyl aziridines, CuAAC reaction, deprotection

Zemītis, J., Kreituss, I., Turks, M., Bizdēna, Ē., Trapencieris, P. Triazolylmethyl Aziridines with Various Side Chain. Latvijas Ķīmijas Žurnāls, 2012, Nr.1, 79.-79.lpp. ISSN 0868-8249.

Publikācijas valoda
English (en)
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