Click, Substitute and Fluoresce: Synthesis and Applications of 2,6-Di-(1,2,3-triazolyl)-purine Nucleosides
XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids: Poster Abstracts 2012
Irina Novosjolova, Armands Kovaļovs, Inga Bižāne, Ērika Bizdēna, Māris Turks

A novel class of ditriazolylpurine nucleosides were ob-tained from 2,6-diazido precursors via copper catalyzed azide-alkyne cycloaddition. These intermediates ap-peared to be very reactive towards N- and S-nucleophiles and thus selectively gave C(6)-substituted analogs with triazolyl moiety at C(2)-position. The latter products exhibit interesting fluorescence properties.


Atslēgas vārdi
ditriazolylpurine nucleosides, 1,3-dipolar cycloaddition reaction, fluorescence
Hipersaite
http://www.is3na.org/assets/events/Category%203-Nucleos%28t%29ide%20Probes%20%28109-153%29.pdf#page=26

Novosjolova, I., Kovaļovs, A., Bižāne, I., Bizdēna, Ē., Turks, M. Click, Substitute and Fluoresce: Synthesis and Applications of 2,6-Di-(1,2,3-triazolyl)-purine Nucleosides. No: XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids: Poster Abstracts, Kanāda, Montreal, 5.-9. augusts, 2012. [S.l.]: IS3NA, 2012, 134.-134.lpp.

Publikācijas valoda
English (en)
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