Synthesis of Novel 2- and 6-Alkyl/Arylthiopurine Derivatives

Proceedings of 26th International Symposium on Organic Chemistry of Sulfur 2014
Irina Novosjolova, Ērika Bizdēna, Māris Turks

We have compared the reactivity of 2,6-bis-triazolylpurine, 2,6-dichloropurine and 2,6-diazidopurine nucleosides in the nucleophilic aromatic substitution reactions with thiols. In this way various 2- and 6-alkyl/arylthiopurine derivatives are available for further applications in medicinal chemistry which will be discussed in details.

Atslēgas vārdi
bis-triazolyl derivatives, purine nucleosides

Novosjolova, I., Bizdēna, Ē., Turks, M. Synthesis of Novel 2- and 6-Alkyl/Arylthiopurine Derivatives. No: Proceedings of 26th International Symposium on Organic Chemistry of Sulfur, Turcija, Istanbul, 24.-29. augusts, 2014. Istanbul: 2014, 19.-19.lpp.

Publikācijas valoda
English (en)