1,2,3-Triazole Moiety- a Useful Tool for Functionalization of Purine Nucleosides

Riga Technical University 57th International Scientific Conference "Materials Science and Applied Chemistry" (MSAC 2016): Proceedings and Programme 2016
Kristers Ozols, Dace Cīrule, Irina Novosjolova, Ērika Bizdēna, Māris Turks

Azide-alkyne 1,3-dipolar cycloaddition has been employed for the preparation of purine 2,6-bis-(1,2,3-triazol-1-yl) derivatives. These compounds are excellent substrates for SNAr reactions and hence have been used to prepare nucleophilic substitution products in good to excellent yields. Some of the obtained products exhibit fluorescent properties.

Atslēgas vārdi
Purine derivatives, nucleosides, fluorescent nucleosides, adenosine analogues, Click chemistry
Hipersaite
https://conferences.rtu.lv/index.php/MSAC/MSAC2016/paper/viewFile/36/20

Ozols, K., Cīrule, D., Novosjolova, I., Bizdēna, Ē., Turks, M. 1,2,3-Triazole Moiety- a Useful Tool for Functionalization of Purine Nucleosides. No: Riga Technical University 57th International Scientific Conference "Materials Science and Applied Chemistry" (MSAC 2016): Proceedings and Programme, Latvija, Riga, 21.-21. oktobris, 2016. Riga: RTU Press, 2016, 139.-142.lpp. ISBN 978-9934-10-861-7.

Publikācijas valoda
English (en)