Publikācijas veids | Raksts konferenču tēžu krājumā |
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Pamatdarbībai piesaistītais finansējums | Pētniecības projekti |
Aizstāvēšana: | , |
Publikācijas valoda | English (en) |
Nosaukums oriģinālvalodā | Fluorescent Triazolyl Purines and their Nucleoside Congeners |
Pētniecības nozare | 1. Dabaszinātnes |
Pētniecības apakšnozare | 1.4. Ķīmija |
Autori |
Māris Turks
Ērika Bizdēna Dace Cīrule Zigfrīds Kapilinskis Irina Novosjolova Kristers Ozols Armands Sebris Andrejs Šišuļins Jānis Miķelis Zaķis |
Atslēgas vārdi | purines, azoles, SNAr reactions |
Anotācija | Further investigations lead to the use of diazidopurine as a substrate for SNAr reactions. Depending on the nature of N(9) substituent of purine, the incoming nucleophile and the experimental conditions, selectivity towards differently substituted compounds can be achieved. This is mainly determined by azide-tetrazole tautomerism 1-A ↔ 1-T. We have found that 2-(1,2,3-triazolyl)adenine/adenosine analogs and their regioisomers possess excellent fluorescent properties. These purine derivatives can be applied both for fluorescent oligonucleotide synthesis and for OLED technologies. Moreover, the developed chemistry permits synthesis of novel purine conjugates containing 5-membered heterocycles at C(2). |
Hipersaite: | https://www.chemie.uni-hamburg.de/veranstaltungen/6gpcoc/GBP_Abstracts.pdf ![]() |
Atsauce | Turks, M., Bizdēna, Ē., Cīrule, D., Kapilinskis, Z., Novosjolova, I., Ozols, K., Sebris, A., Šišuļins, A., Zaķis, J. Fluorescent Triazolyl Purines and their Nucleoside Congeners. No: German-Polish-Baltic Conference on Organic Chemistry : Book of Abstracts, Vācija, Hamburg, 15.-19. maijs, 2018. Hamburg: Hamburger Print Service, 2018, 59.-59.lpp. ISBN 978-3-00-058883-9. |
Pilnais teksts | Pilnais teksts |
ID | 27509 |