Synthesis of 2-Triazolylpurine Phosphonates
Chemistry of Heterocyclic Compounds 2021
Zigfrīds Kapilinskis, Irina Novosjolova, Ērika Bizdēna, Māris Turks

A series of novel compounds containing triazole and phosphonate moieties were obtained under mild conditions. Reactions of 2,6-bis-(triazolyl)purine acyclic nucleoside phosphonates, in which triazole ring at C-6 atom of purine was acting as a good leaving group, and N- or S-nucleophiles allowed to obtain the respective 2-triazolylpurine phosphonates in 62–87% yields.

Atslēgas vārdi
2,6-bis(triazolyl)purines, purine phosphonates, 2-triazolylpurines, nucleophilic aromatic substitution

Kapilinskis, Z., Novosjolova, I., Bizdēna, Ē., Turks, M. Synthesis of 2-Triazolylpurine Phosphonates. Chemistry of Heterocyclic Compounds, 2021, Vol. 57, No. 1, 55.-62.lpp. ISSN 0009-3122. e-ISSN 1573-8353. Pieejams: doi:10.1007/s10593-021-02867-w

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English (en)
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