The potential application of electrolysis for drinking water disinfection has been investigated. Water treatment with electrolysis was performed using TinO2n-1 containing ceramic anode and Escherichia coli and Pseudomonas fluorescens as a model organism for disinfection experiments. Water solution containing chloride and bromide ions can be disinfected by electrolysis using ceramic electrodes that contain TinO2n-1 - number of bacteria colony forming units dramatically decreases in electrolysed solutions due to released chlorine and bromine. During the electrolysis process pH of model solutions increases due to formation of hydrogen. Oxidation – reduction potential increases during electrolysis process if halogen ions are used and decreases if sulphate ions are used. When using a TinO2n-1 electrode in the electrolysis process with the presence of chloride ions, in concentration range which is common in raw waters, enough active chlorine can be created to kill more than 99% of E. coli within 15 minutes. The mathematical model for prediction of disinfection efficacy of Escherichia coli with electrolysis process has been developed.