RTU Research Outputs and Resources: Reasearch Staff

Information about Author

Name, Surname:

Aigars Jirgensons

Department:

(32300) Ķīmijas un ķīmijas tehnoloģijas institūts

Scientific Degree:

Doktors

E-mail:

Aigars.Jirgensons(at)rtu.lv

Publications

132 items found, displaying 51 to 60.

Crystal Structure of Plasmodium Falciparum Proplasmepsin IV: The Plasticity of Proplasmepsins
(2016)

R. Recacha, Kristaps Jaudzems, I. Akopjana, Aigars Jirgensons, K. Tars
Scientific article indexed in SCOPUS or WOS database

A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus Aureus
(2016)

A. Gupta, C. Monteferrante, Dace Rasiņa, G. Leitis, C. P. Randall, J. H. Tomlinson, Aigars Jirgensons, W. H. F. Goessens, J. P. Hays, A. J. O`neill
Scientific article indexed in SCOPUS or WOS database

Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones as Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV
(2016)

Dace Rasiņa, Mārtiņš Otikovs, J. Leitans, R. Recacha, O. V. Borysov, I. Kanepe-Lapsa, I. Domraceva, T. Pantelejevs, K. Tars, M. J. Blackman, Kristaps Jaudzems, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Synthesis of α-Ethynyl Glycines
(2016)

Jekaterina Boļšakova, Aigars Jirgensons
Publication (anonimusly reviewed) in a journal with an international editorial board indexed in other databases

Synthesis of Alkynyl-Glycinols by Lewis Acid Catalyzed Propargylic Substitution of Bis-Imidates
(2016)

Jekaterina Sirotkina, Liene Grigorjeva, Aigars Jirgensons
Publication (anonimusly reviewed) in a journal with an international editorial board indexed in other databases

Allylic Amination via Acid Catalyzed Leaving Group Activation
(2016)

Marija Skvorcova, Aigars Jirgensons
Publication (anonimusly reviewed) in a journal with an international editorial board indexed in other databases

Amide Directed Protolytic Cleavage of Cyclopropane C-C Bond
(2016)

Marija Skvorcova, Aigars Jirgensons
Conference paper

Pyrrolidine Derivatives via Protolytic Cleavage of Cyclopropane C-C Bond
(2016)

Marija Skvorcova, Aigars Jirgensons
Conference paper

N-Acylsulfonamide as Directing Group and Internal Oxidant in Ruthenium Catalyzed C-H Activation/ Annulation Reactions
(2016)

Elīna Līdumniece, Dace Rasiņa, Aigars Jirgensons
Conference paper

Synthesis of 4-Alkynyl 2-Oxazolines via the Ritter Reaction
(2016)

Konstantinos Grammatoglou, Jekaterina Boļšakova, Aigars Jirgensons
Conference paper

Information about Author

Publications

Crystal Structure of Plasmodium Falciparum Proplasmepsin IV: The Plasticity of Proplasmepsins
(2016)

A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus Aureus
(2016)

Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones as Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV
(2016)

Synthesis of α-Ethynyl Glycines
(2016)

Synthesis of Alkynyl-Glycinols by Lewis Acid Catalyzed Propargylic Substitution of Bis-Imidates
(2016)

Allylic Amination via Acid Catalyzed Leaving Group Activation
(2016)

Amide Directed Protolytic Cleavage of Cyclopropane C-C Bond
(2016)

Pyrrolidine Derivatives via Protolytic Cleavage of Cyclopropane C-C Bond
(2016)

N-Acylsulfonamide as Directing Group and Internal Oxidant in Ruthenium Catalyzed C-H Activation/ Annulation Reactions
(2016)

Synthesis of 4-Alkynyl 2-Oxazolines via the Ritter Reaction
(2016)

Supervised Dissertations

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Development of New Synthetic Methods based on Electrochemical Oxidation of Stannylmethylethers and Furan Derivatives
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Electrophile-Induced Cyclopropane Reactions with Nucleophiles
(2018)

Development of Malarial Aspartic Protease Inhibitors
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-Heteroatom Bond Formation In Lewis Acid Catalysed Allylic Substitution Reaction
(2013)

Projects

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika

Information about Author

Publications

Crystal Structure of Plasmodium Falciparum Proplasmepsin IV: The Plasticity of Proplasmepsins (2016)

A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus Aureus (2016)

Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones as Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV (2016)

Synthesis of α-Ethynyl Glycines (2016)

Synthesis of Alkynyl-Glycinols by Lewis Acid Catalyzed Propargylic Substitution of Bis-Imidates (2016)

Allylic Amination via Acid Catalyzed Leaving Group Activation (2016)

Amide Directed Protolytic Cleavage of Cyclopropane C-C Bond (2016)

Pyrrolidine Derivatives via Protolytic Cleavage of Cyclopropane C-C Bond (2016)

N-Acylsulfonamide as Directing Group and Internal Oxidant in Ruthenium Catalyzed C-H Activation/ Annulation Reactions (2016)

Synthesis of 4-Alkynyl 2-Oxazolines via the Ritter Reaction (2016)

Supervised Dissertations

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors (2023)

Development of New Synthetic Methods based on Electrochemical Oxidation of Stannylmethylethers and Furan Derivatives (2023)

Development of Malarial Enzyme Inhibitors (2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase (2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols (2020)

Electrophile-Induced Cyclopropane Reactions with Nucleophiles (2018)

Development of Malarial Aspartic Protease Inhibitors (2016)

Development of Malarial Protease PfSUB1 Inhibitors (2014)

C-Heteroatom Bond Formation In Lewis Acid Catalysed Allylic Substitution Reaction (2013)

Projects

Atbalsts RTU doktora studiju īstenošanai - 2 Izglītība

Methods of critical infrastructure control Enerģētika

Crystal Structure of Plasmodium Falciparum Proplasmepsin IV: The Plasticity of Proplasmepsins
(2016)

A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus Aureus
(2016)

Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones as Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV
(2016)

Synthesis of α-Ethynyl Glycines
(2016)

Synthesis of Alkynyl-Glycinols by Lewis Acid Catalyzed Propargylic Substitution of Bis-Imidates
(2016)

Allylic Amination via Acid Catalyzed Leaving Group Activation
(2016)

Amide Directed Protolytic Cleavage of Cyclopropane C-C Bond
(2016)

Pyrrolidine Derivatives via Protolytic Cleavage of Cyclopropane C-C Bond
(2016)

N-Acylsulfonamide as Directing Group and Internal Oxidant in Ruthenium Catalyzed C-H Activation/ Annulation Reactions
(2016)

Synthesis of 4-Alkynyl 2-Oxazolines via the Ritter Reaction
(2016)

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Development of New Synthetic Methods based on Electrochemical Oxidation of Stannylmethylethers and Furan Derivatives
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Electrophile-Induced Cyclopropane Reactions with Nucleophiles
(2018)

Development of Malarial Aspartic Protease Inhibitors
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-Heteroatom Bond Formation In Lewis Acid Catalysed Allylic Substitution Reaction
(2013)

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika