Tailoring the Degradation of Hydroxyapatite/Poly (Vinyl Alcohol) Composites
European Cells and Materials 2015
Līga Stīpniece, Kristīne Šalma-Ancāne, Vitālijs Rjabovs, Līga Bērziņa-Cimdiņa

The overall goal of this work is to develop HAp/PVA composites for medical application. PVA has been exploited for use in drug delivery due to its high hydrophilicity, ease of processing, mechanical and thermal stability, and its non-toxic and biodegradable nature. Depending on the processing parameters, PVA may dissolve instantly upon contact with aqueous mediums. Thus, there has been limited use of PVA composites in biomedical applications. However, those shortcomings could be eliminated by modification of the composites through various post-treatments to alter the physicochemical properties, thereby producing a structure with poorer solubility characteristics, which is suitable for biomedical devices. Moreover, PVA can be chemically modified to provide various functionalities.


Atslēgas vārdi
hydroxyapatite, poly (vinyl alcohol), spray drying, degradation
Hipersaite
http://www.ecmjournal.org/journal/supplements/vol029supp01/pdf/vol029supp01a065.pdf

Stīpniece, L., Šalma-Ancāne, K., Rjabovs, V., Bērziņa-Cimdiņa, L. Tailoring the Degradation of Hydroxyapatite/Poly (Vinyl Alcohol) Composites. European Cells and Materials, 2015, Vol. 29, No. 1, 65.-65.lpp. ISSN 1473-2262.

Publikācijas valoda
English (en)
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