Biological Activity Profile of Triazolylpurine Nucleosides

16th Symposium on Chemistry of Nucleic Acid Components: Collection Symposium Series (M.Hocek, Ed.) 2014
Irina Novosjolova, Ērika Bizdēna, Ilona Mandrika, Ramona Petrovska, Jānis Kloviņš, Māris Turks

The biological activity of novel 2,6-bis-(1,2,3-triazol-1-yl)purine, N6-substituted-2-(1,2,3-triazol-1-yl)adenine and 6-alkyl/arylthio-2-(1,2,3-triazol-1-yl)purine nucleosides were studied. Novel 2,6-bis-triazolyl- and 2-triazolyl purine nucleosides act as agonists of adenosine and purine receptors and some of the mentioned nucleosides possess also antiviral activity.

Atslēgas vārdi
purine nucleosides, bis-triazolyl derivatives, biological activity

Novosjolova, I., Bizdēna, Ē., Mandrika, I., Petrovska, R., Kloviņš, J., Turks, M. Biological Activity Profile of Triazolylpurine Nucleosides. No: Collection Symposium Series. Vol.14. M.Hocek red. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2014. 337.-339.lpp. ISBN 978-80-86241-50-0.

Publikācijas valoda
English (en)